PDF files contain metadata and full text, while the TIFF format (Tagged Image File) is a popular format for high color depth (32 bit) images. The format was originally created by the company Aldus for use with PostScript printing. The difference is that a PDF with the text file can be much larger.
Basically, it depends on how you will use and store the documents you have created. For most users who are adding text in their documents, the PDF prooves to be a better option. It is a universally accepted format that any recipient can view using the free Acrobat Reader utility. If the creation of primary documents is handled in Microsoft Word, for example, you want to convert your finished product into a PDF before sharing. This ensures that the file remains the same font format and content of your choice, regardless of the version of Word to their respective readers might have. It is also a file format offers much safer than the ability to control factors such as who can read or modify the document.
PDF is also better equipped to handle multi-page documents and if needed can be converted back to its original format say coverting pdf files to msword. Each original page is displayed as a separate page within a single PDF file. TIFF supports multiple pages, but lacks important features, such as the ability to specify multi-layer relationships of different pages.
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